Tuesday, March 13, 2012

Cocoa may help diabetes, heart failure

Patients with advanced heart failure and type 2 diabetes showed improvement after three months of consuming epicatechin-enriched cocoa, U.S. researchers said.

Dr. Francisco J. Villarreal of University of California, San Diego, said epicatechin is a flavonoid found in dark chocolate.

The researchers examined five profoundly ill patients with major damage to skeletal muscle mitochondria -- structures responsible for most of the energy produced in cells. These "fuel cells" are dysfunctional as a result of both type 2 diabetes and heart failure, leading to abnormalities in skeletal muscle, Villarreal said.

Patients with heart failure and diabetes experience abnormalities in both the heart and skeletal muscle that can result in impaired functional capacity. They often complain of shortness of breath, lack of energy and have difficulty walking even short distances.

Trial participants consumed dark chocolate bars and a beverage with a total epicatechin content of approximately 100 milligram per day for three months. Biopsies of skeletal muscle were conducted before and after treatment.
After three months, the researchers looked at changes in mitochondria volume and the abundance of cristae, are internal compartments of mitochondria necessary for efficient function of the mitochondria.
"The cristae had been severely damaged and decreased in quantity in these patients," Villarreal said in a statement. "After three months, we saw recovery -- cristae numbers back toward normal levels, and increases in several molecular indicators involved in new mitochondria production."

The findings were published in the journal Clinical and Translational Science.

8 comments:

  1. The Only insightderm.com website is a great place to gather insightderm information.
    here is get more information.

    San Diego dermatology
    San Diego dermatologist
    San Diego Botox

    ReplyDelete
  2. Nice post! I must thank you for this informative read. I hope you will post again soon.
    Kind regard
    Wire Harness Manufacturers

    ReplyDelete
  3. If you want to find more information how Dermatology in delhi can benefit you then you can visit Dermatologist in delhi

    ReplyDelete
  4. Thank you for providing clear information on this. you can also refer Wire Harness Manufacturers

    ReplyDelete
  5. You have done a great job. I will definitely dig it and personally recommend to my friends. I am confident they will be benefited from this site. Dermatologia
    Dermatologia

    ReplyDelete
  6. Likes substantially raise the level of recognition of one's site and while using the right assortment count; instagram buy likes many folks are going to be keen on your account. The companies that offer these goods and products and services, will present you with non-automated or robot likes and provide you with major Instagram likes. The great issue associated with this is they are really immediately despatched in your account to ensure that you do not have to have to wait that considerably. And when you are a organization, escalating your Instagram likes will probably be useful.

    ReplyDelete
  7. Hi there, I found your blog via Google while searching for such kinda informative post and your post looks very interesting for me.
    Buy Facebook Likes Cheap

    ReplyDelete
  8. Find best dermatologist in Mumbai & View experience, reviews, Consulting timings & contact details of Skin Specialist in Mumbai.

    ReplyDelete